Although Aloe is generally considered to be a healing plant or herbal remedy it can be harmful to pets if ingested. Aloe Latex (Aloe Juice) is a yellowish, bitter liquid that containing Aloin that can be found just under the skin of the Aloe leaf and acts as a powerful laxative. Once ingested, aloin increases symmetrical contraction and relaxation of muscles of the colon inducing bowel movements. Aloin also opens the chloride channels of the colonic membrane preventing the colon from re-absorbing water from the gastrointestinal tract, leading to even softer stools. Aloe latex also has an irritative effect on the large intestines which when combined with its properties as a natural laxative can lead to severe diarrhea, putting the pet at risk for dehydration. The University of Wisconsin confirms this and lists aloe vera as a toxic plant noting that consumption of large amounts of aloe vera latex has caused diarrhea so severe that it resulted in dehydration and electrolyte imbalances. There is also the possibility of contact dermatitis to the mouth, throat, nose and face in animals with sensitive skin or allergies to latex. The ingestion of Aloe by a pet is generally not considered to be life threatening and the symptoms will typically be limited to mild to severe gastrointestinal upset (vomiting, diarrhea), a change in urine color, and tremors. Because aloin can potentially cause uterine contractions, pregnant animals should not be allowed access to areas containing Aloe vera plants.